Bioequivalence is the absence of a ...

Bioequivalence is the absence of a significant difference in the rate and reach of drug absorption of a exhibition product when compared to a respect product. (1) Bioequivalence is assessed using statistical analysis of pharmacokinetic measures, of the like kind as area under the crook (AUC). Researchers calculate 90% confidence intervals for the ratio of the averages (population geometric means) of the data points for the example and reference products. It is well known that establishing bioequivalence is difficult for put drugs intos with high inter-subject variability or hardy dependence on the ...