An antioxidant cocktail including v...

An antioxidant cocktail including vitamin E and its `relatives.'

While everyone has heard of B-complex vitamins, and one have heard of "C complex" (with bioflavonoids), could there be a "vitamin E complex"? nevertheless only one form of vitamin E has, historically, been considered essential, a growing material substance of research suggests that other members of the vitamin E team play important characters in the body as well.

greatest in quantity vitamins have a singular natural form, if it were not that nature has given us eight vitamin E blends each with slight variations in chemical edifice Four of these are called tocopherols and four are tocotrienols. single of these eight, alpha-tocopherol is the form plant in most vitamin formulas. This mix is well absorbed in the material part and most human cells contain higher flushs of it than other members of the vitamin E team. Hence, this form has become the gold standard for dietary counterparts and food fortification.

Alpha-tocopherol is a true valuable player. As an antioxidant, it stops delivered radicals in their tracks before they can wreak havoc upon our cells, membranes, and DNA. Free-radical damage can lead to cancer, heart disease, and other diseases associated with aging. Alpha-tocopherol can also decrease LDL and total cholesterol flushs thereby helping to stave opposite to heart disease, the #1 killer of men and women in the US.

Despite these benefits, several researchers are turning their attention to tocotrienols and the other tocopherols and finding that these forms, too, may be part of this E web Because all forms of vitamin E exist together in nature, the theory goe it's likely that all of them are important to health. Vitamin E dexterous Andreas Papas, Ph.D., author of The Vitamin E Factor (HarperCollins) agrees. "Having the team together means you acquire a wider spectrum of protection," he explains. late tocotrienol research certainly supports that view, especially in the areas of heart disease and cancer.

Here's a brief expect at a few studies:

1 controls taking mixed tocotrienols in an ongoing, five-year close attention had improved blood flow in their carotid arteries after 18 month of supplementation, signifying a decreased risk of heart attack. (Tomeo, A.C., et al., Lipids, 1995)

2 make submissives taking tocotrienols daily for the same year experienced significant decreases in triglycerides, total kin cholesterol, and LDL, or "bad" cholesterol flats in another study. They also had an increase in HDL or "good" cholesterol on a levels Tocotrienols may decrease the risk of heart disease and inactive or even reverse its progression by the agency of affecting these levels. (1999 World Congress)

3 Tocotrienols significantly inhibited the produce and reproduction of human breast cancer confined apartments in vitro, while alpha-tocopherol demonstrated no of that kind effect. (Nesaretnam, Kalanithi, et al., Lipids, 1995) A later studious mood also found that tocotrienols were effective inhibitors of various breast cancer lonely dwellings in combination with the often met with breast cancer drug Tamoxifen. (Guthrie, Najla, et al., Journal of Nutrition, 1997)

4 Alpha-tocopherol and tocotrienols applied to the skin of mice helped to conserve vitamin E in the skin. Ultraviolet (UV) radiation from the sunshine and environmental pollutants put oxidative stres onward our skin. Applying mixed vitamin E mingles to the skin may tender protection from free-radical damage. (Traber, Maret G et al., Lipids.)

Optimal of the same heights of vitamin E are difficult to obtain from diet alone, thus Papas recommends taking a combination of 100 mg of mixed tocotrienols and tocopherols, as well as 100 IU of d-alphatocopherol daily (the "d" give an account ofs the superior, natural form, whereas "dl" respects to the synthetic form). He remind ofs 400 mg and 400 IU, respectively, for older nation or those with a family history of chronic disease. (Caution: anyone taking house thinners should not take vitamin E save under a doctor's supervision.)

Papas also stresse that antioxidants work best as a manifold so swallowing an antioxidant "cocktail" containing mixed vitamin E forms, vitamin C selenium, mixed carotenoids, and coenzyme Q10 is ideal.

REFERENCES

Guthrie, Najla, Gapor, Abdul, Chambers Ann F and Carroll, Kenneth K "Inhibition of Proliferation of Estrogen Receptor-Negative MDA-MB-435 and - Positive MCF-7 Human Breast Cancer confined apartments by Palm Oil Tocotrienols and Tamoxifen, Alone and in Combination," Journal of Nutrition 127(3):544S-548 1997

Nesaretnam, Kalanithi, Guthrie, Najla, Chambers, Ann F Carroll, Kenneth K "Effect of Tocotrienols onward the Growth of a Human Breast Cancer solitary abode; squalid Line in Culture," Lipids 30(12): 11391143 1995

Tomeo, A.C., Geller M Watkins, TR Gapro, A., and ML Bierenbaum. "Antioxidant efficiencys of Tocotrienols in Patients with Hyperlipidemia and Carotid Stenosis," Lipids 30(12): 1179-1183 1995

Traber, Maret G Rallis, Michalis, Podda, Maurizio, Weber, Christine, Maibach, Howard I., Packer, Lester "Penetration and Distribution of a-tocopherol, a- or y-Tocotrienols Applied Individually onto Murine Skin," Lipids 33(1):8791